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New $10.8M NIH Grant

Friday, January 26, 2018

Professors Mei He and Arghya Paul are involved in a project that has been awarded a $10.8 million dollar grant for research into cancer, neurological disorders, and lung and heart disease. This is the second phase of grant funding that has been provided through The University of Kansas' Center for Molecular Analysis of Disease Pathways, a National Institutes of Health Center of Biomedical Research Excellence (COBRE). The main PI on the grant is Professor Susan LunteRalph N. Adams Distinguished Professor of Chemistry and Pharmaceutical Chemistry and Director of the Adams Institute for Bioanalytical Chemistry. 

CMADP's mission is "to brings together junior and senior faculty from the physical, biological, and pharmaceutical sciences at the University of Kansas and other academic institutions in Kansas to conduct multidisciplinary research to develop and implement cutting-edge technologies for elucidating the genetic, chemical, and physical mechanisms of biological processes involved in disease."

"The center’s three core facilities were established during Phase I and are focused on providing tools for junior investigators working on the development or application of new enabling technologies to study disease pathway. These facilities are also available to researchers at KU and other universities in the region:

  • The Genome Sequencing Core provides researchers with next-generation sequencing technologies, as well as experimental design and analysis of sequence data. The core is involved in the identification of genetic (genotypic) elements that underlie the disease and disease pathways.
  • The Microfabrication & Microfluidics Core makes resources and personnel available for the production of micro- and nano-scale devices to be used by project investigators for their studies. Equipment and training are available to investigators for the fabrication of devices for biomedical, biophysical and bioanalytical studies related to disease pathways.
  • The Synthetic Chemical Biology Core offers expert design of molecular probes and synthesis of both small molecules and peptides, with an emphasis on the generation of fluorescent and other tagged molecules, as well as bioassays of molecular probes, including in vitro whole cell assays and in vivo assays using zebrafish."

To read the full article, click here


From left, faculty leadership for the COBRE grant to University of Kansas’ Center for Molecular Analysis of Disease Pathways: Blake Peterson, Susan Lunte, Erik Lundquist. Credit: KU



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